Pufferfish, lungfish, frogs, and the C-Value Paradox. (pp. 33-34)The complexity of genomes
Reassociation kinetics (C0t curves). Highly repetitive DNA, moderately repetitive DNA, unique sequence DNA. (pp. 34-35)Variation in genome size
Junk DNA explains the variations in genome size. The C-Value Enigma. You don't need new genes to explain complexity. (pp. 35-37)Instantaneous genome doubling
Polyploidy. Brassica species. Organisms can tolerate extra DNA. (pp. 38-39)The Onion Test
Modern evolutionary theoryThe Onion test is a way of testing your junk DNA hypotheses. (pp. 39-40) [The Onion Test]
Random genetic driftEvolution is a change in the frequency of alleles in a population. Adaptation, fixation, postive selection, negative selection, purifying selection. (pp. 40-41) [Is the Modern Synthesis effectively dead?] [Kevin Laland's view of "modern" evolutionary theory (again)]
Beanbag genetics and population genetics. Fixation by random genetic drift. (pp. 41-43) [On the importance of random genetic drift in modern evolutionary theory] [Evolution by chance] [The role of chance in evolution] [One philosopher's view of random genetic drift] [A philosopher's view of random genetic drift]Neutral Theory
Nearly neutral TheoryKimura and the promotion of the neutral theory. Random genetic drift as a major cause of evolution. (pp. 43-44) [Celebrating 50 years of Neutral Theory]
Ohta and the nearly neutral Theory. The fixation of slightly deleterious alleles.(pp. 44-45)Population genetics
On the evolution of sloppy genomesPopulation size and selection coefficients. Probability of fixation. Population size and the fixation of slightly deleterious alleles. Drift-Barrier Hypothesis. (pp. 45-49) [Learning about modern evolutionary theory: the drift-barrier hypothesis]
Box: Are humans are still evolving? (pp. 49-50)
Bacteria have small genomesInsertions, deletions, and random genetic drift. (pp. 50-54) [Evolution by Accident]
Box: Chromosome dynamics (p. 54) [Segmental duplications in the human genome]
Why do bacteria have small genomes? (pp. 54-56)
Notes for Chapter 2 (pp. 318-320)
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